WebOct 22, 2013 · REACH is a prospective, phase I/II open-label dose escalation trial of hydroxyurea for children with confirmed SCA between 12 months and 10 years of age. The short-term goal is to obtain critical pilot data regarding the feasibility, safety, and benefit of hydroxyurea for children with SCA in multiple distinct research settings in Africa. WebJul 16, 2024 · To determine the effects of ruxolitinib compared with an investigator’s choice of therapy from 10 commonly used options among these patients, researchers conducted …
Novartis announces first data from REACH3 trial showing …
WebBackground: Based on the hypothesis of synergistic effect of avelumab with cetuximab and radiotherapy, this new combination is tested in a randomised trial against two well-established standard of care (SOC) in locally advanced squamous-cell carcinoma of the head and neck (LA-SCCHN). Methods: This phase III trial comprises two cohorts of … WebSep 24, 2024 · The trial also showed a trend at this interim analysis towards improved overall survival (OS). However, the data are still immature and the trial will continue to assess OS as a key secondary endpoint. ... for Lynparza with abiraterone to become a new 1st-line option for patients regardless of their biomarker status and reach a broad … high field energy
[article3] REACH - Registration, Evaluation, Authorisation and ...
WebBackground: Chronic obstructive pulmonary disease (COPD) has become a leading cause of morbidity and mortality in China, with tobacco smoke, air pollution, and occupational biohazards being the major risk factors. Objectives: The REACH trial is a multicenter, prospective, randomized controlled trial undertaken in China to assess the safety and … WebJun 18, 2015 · Ramucirumab versus placebo as second-line treatment in patients with advanced hepatocellular carcinoma following first-line therapy with sorafenib (REACH): a … Web8 hours ago · Delhi chief minister Arvind Kejriwal alleged that the ‘No 2, No 3' ministers of his party have been targetted in order to reach him, adding that he knew he would be next in … how historically accurate is the series reign